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Table 2 Detoxification genes upregulated in Rperm-S, C-S and Rperm-C

From: Investigating the molecular basis of multiple insecticide resistance in a major malaria vector Anopheles funestus (sensu stricto) from Akaka-Remo, Ogun State, Nigeria

S/N

Transcript name

Gene name

Rperm-S FC

C-S FC

Rperm-C FC

Ortholog in An. gambiae

Description

1

CUST_762_PI426302897

Afun000762

5.19

3.83

2.53

AGAP006733

THO complex subunit 4

2

CUST_2376_PI406199772

CD578215.1

17.81

43.40

  

Cuticle protein

3

CUST_2375_PI406199772

CD578215.1

14.75

36.74

  

Cuticle protein

4

CUST_15266_PI426302897

Afun015266

2.44

2.88

 

AGAP010911-PA

Carboxylesterase

5

CUST_10482_PI426302897

Afun010482

18.00

65.91

 

AGAP008449-PA

Cuticle protein

6

CUST_3752_PI406199772

CD577507.1

3.56

5.87

  

Cuticle protein

7

CUST_13390_PI426302897

Afun013390

4.11

3.47

 

AGAP000344-PB

Cuticular protein rr-1

8

CUST_15708_PI406199769

Combined_c8336

2.25

   

Glucosyl glucuronosyl transferases

9

CUST_7571_PI426302897

Afun007571

2.44

  

AGAP007920-PA

Glucosyl glucuronosyl transferases

10

CUST_15707_PI406199769

Combined_c8336

2.10

   

Glucosyl glucuronosyl transferases

11

CUST_8617_PI426302897

Afun008617

2.02

  

AGAP005222-PB

Cytochrome b561

12

CUST_15122_PI426302897

Afun015122 (GSTU2)

4.25

  

AGAP003257-PA

Glutathione S-transferase gst

13

CUST_10134_PI426302897

Afun010134

4.75

  

AGAP006711-PA

Chymotrypsin 1

14

CUST_1378_PI406199798

AGAP001405-RA_2R

 

2.42

 

AGAP001405-RA_2R

Short-chain dehydrogenase

15

CUST_484_PI406199788

gb-CYP9J3

 

2.30

  

Cytochrome p450

16

CUST_5277_PI406199769

Combined_c2672

 

2.20

  

Cuticular protein 97eb

17

CUST_36_PI406199775

COEAE6O

 

2.15

 

AGAP002863-PA

Carboxylesterase

18

CUST_5_PI406199775

CYP6AA4

 

3.49

  

Cytochrome p450

19

CUST_11060_PI406199798

AGAP011431-RA_3L

 

2.02

 

AGAP011431-RA_3L

Trypsin 5

20

CUST_3941_PI406199772

CD577405.1 (GSTS1)

 

2.00

  

Glutathione-S-transferase

21

CUST_4873_PI406199772

BU039010.1

 

2.13

  

Cytochrome c

22

CUST_8525_PI426302897

Afun008525

 

20.18

 

AGAP000047-PA

Cuticle protein rr-1

23

CUST_3943_PI406199772

CD577404.1

 

2.38

  

Glutathione S-transferase

24

CUST_3751_PI406199772

CD577507.1

 

2.32

  

Cuticle protein

25

CUST_13027_PI406199798

AGAP012291-RA_3L

 

2.42

 

AGAP012291-RA_3L

Cytochrome p450

26

CUST_2644_PI406199772

CD578079.1

 

2.70

  

Trypsin

27

CUST_2643_PI406199772

CD578079.1

 

2.98

  

Trypsin

28

CUST_10994_PI426302897

Afun010994 (CYP6P9b)

 

14.48

 

AGAP002867-PA

Cytochrome p450

29

CUST_2814_PI406199769

AGAP004164-RC_glutatathione-S-transferase

  

2.09

AGAP004164-RC_glutatathione-S-transferase

Glutathione-S-transferase

30

CUST_2245_PI406199798

CYP6P2

  

2.47

 

Cytochrome p450

31

CUST_4637_PI406199798

Afun014849

  

2.03

AGAP011507-PA

Esterase fe4

32

CUST_10523_PI406199798

CYP6P9a

  

2.92

 

Cytochrome p450

  1. Abbreviation: FC, fold change