Fig. 2

The gross specimens of liver and spleen (a), liver and spleen indexes (b), serum levels of AST and ALT (c), liver histopathology stained with H&E (d), and liver pathological semi-quantitation (e) of different groups. The measurements were performed on day 22 after T. spiralis infection and/or on day 13 after PbANKA infection. Shown are the liver of an uninfected mouse, a T. spiralis-mono-infected mouse, a PbANKA-mono-infected mouse, and a T. spiralis + PbANKA-co-infected mouse. Original magnifications were 200× (Scale-bar: 100 µm), 400× (Scale-bar: 50 µm), and 1000× (Scale-bar: 20 µm). Data are expressed as the mean ± SD (n = 6 per group). *P < 0.05 and ****P < 0.0001 vs naive mice; ⁺⁺⁺P < 0.001 and ⁺⁺⁺⁺P < 0.0001 vs T. spiralis-mono-infected mice; ^#P < 0.05 and ^##P < 0.01 vs PbANKA-mono-infected mice