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Table 2 Efficacy of alphacypermethrin and chlorfenapyr mixture in insecticide treated nets

From: Anopheles metabolic proteins in malaria transmission, prevention and control: a review

Reference

Camara et al. [226]

Bayili et al. [269]

NʼGuessan et al. [230]

NʼGuessan et al. [228]

Oxborough et al. [231]

Mosquito strain & (location)

An. gambiae (s.s.) (Côte d’Ivoire)

An. gambiae (s.l.) (Burkina Faso)

An. gambiae (s.l.) (Benin)

An. gambiae (s.l.) (Benin)

An. arabiensis (Tanzania)

Pyrethroid resistance intensity (folds)

450.2 (for Alpha). Over 1700 (for deltamethrin)

Over 1000

207 (for Alpha)

207

 

Insecticide

Alpha (mg/m2)

200 on Interceptor®

200 on Interceptor®

200 on Interceptor®

25

25

CFP (mg/m2)

200

200

200

200

100

Alpha + CFP (mg/m2)

100 + 200 on Interceptor® G2

100 + 200 on Interceptor® G2

100 + 200 on Interceptor® G2

25 + 100

25 + 200

25 + 100

Mortality at 72 h# (%)

Alpha

Unwashed

10a

17

20

30

50f

Washed 20 times

11a

10

13

nd

nd

CFP

92b

86d

76

69e

48f

Alpha + CFP

Unwashed

87b,c

78d

71

75e

77e

58f

Washed 20 times

82c

76d

65

nd

nd

nd

Blood-feeding inhibition## (%)

Alpha

Unwashed

ns

26a,b,c

57d

22f

52g

Washed 20 times

ns

15a

47e

nd

nd

CFP

54

21a,c

43e

ns

72g

Alpha + CFP

Unwashed

43

42b

60d

51

35f

76g

Washed 20 times

34

32b,c

50d,e

nd

nd

nd

Personal protection### (%)

Alpha

Unwashed

57a,c

24d

62.5e

39

nd

Washed 20 times

47c

14d

22f

nd

nd

CFP

76b

22d

36.7g

23

nd

Alpha + CFP

Unwashed

71a,b

44d

59.2e

62

58

nd

Washed 20 times

60a

34d

34.4f,g

nd

nd

nd

  1. Abbreviations: Alpha, alphacypermethrin; CFP, chlorfenapyr; ns, not significant, nd: not determined in the study
  2. For each row (#, ## and ###), where provided, numbers in the same column (from the same study) sharing a letter superscript do not differ significantly (P > 0.05). For resistance status of An. arabiensis in Tanzania, percentage mortality of 58 and 76 were observed for lambda cyhalothrin and permethrin (both pyrethroids)