Fig. 2

Gene sets in flatworms. a BUSCO values for the transcriptome assemblies of Psilotrema simillimum (Psi) and Sphaeridiotrema pseudoglobulus (Sps) compared to that in previously published datasets of parasitic flatworms. High proportion of duplicated genes in S. pseudoglobulus and F. gigantica is marked by red asterisk. Abbreviations: Psi, Psilotrema simillimum; Sps, Sphaeridiotrema pseudoglobulus; Fgi, Fasciola gigantica; Fhe, Fasciola hepatica; Csi, Clonorchis sinensis; Ofe, Opisthorchis felineus; Ovi, Opisthorchis viverrini; Sha, Schistosoma haematobium; Sja, Schistosoma japonicum; Sma, Schistosoma mansoni; Tre, Trichobilharzia regenti; Tsz, Trichobilharzia szidati. b Clustering of shared orthologous proteins among free-living and parasitic flatworms. Based on the similarity of protein sets, four clusters are evident. Abbreviated genus/species names are shown at the bottom and on the left-hand side. Abbreviations: Mli, Macrostomum lignano; Sme, Schmidtea mediterranea; Sma, Schistosoma mansoni; Sha, Schistosoma haematobium; Sja, Schistosoma japonicum; Tre, Trichobilharzia regenti; Tsz, Trichobilharzia szidati; Ofe, Opisthorchis felineus; Csi, Clonorchis sinensis; Ovi, Opisthorchis viverrini; Psi, Psilotrema simillimum; Sps, Sphaeridiotrema pseudoglobulus; Fgi, Fasciola gigantica; Fhe, Fasciola hepatica. The color key shows the number of shared orthogroups among the species. c Venn diagram shows the numbers of orthologous groups that are shared by all flatworms (2569), specific for free-living flatworms (M. lignano and S. mediterranea), shared by all 'sporocystoid' (S. mansoni, S. haematobium, S. japonicum, T. regenti, and T. szidati) or 'redioid' (C. sinensis, O. viverrini, O. felineus, F. hepatica and F. gigantica) species, and those that are specific for P. simillimum (13) and S. pseudoglobulus (43)