Fig. 6a–d

Verification of differentially expressed lncRNAs and their putative targets in livers and spleens of mice infected with S. japonicum by reverse transcription-quantitative real-time polymerase chain reaction (RT-qPCR). Relative expression levels of lncRNAs in livers (a) and spleens (b) of mice at 25 days post-infection. Relative expression levels of the putative targets for selected lncRNAs in livers (c) and spleens (d) of mice at 25 days post-infection. The relative expression levels were normalized to glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene expression. XCR1 Chemokine C motif receptor 1, VCAM1 vascular cell adhesion molecule 1, SAMHD1 SAM domain and HD domain 1, CCR5 chemokine C–C motif receptor 5, GLCC1 glucocorticoid-induced transcript 1, IRS1 insulin receptor substrate 1, EXO1 exonuclease 1, FRY furry homolog Drosophila, CCDC137, coiled coil domain containing 137, TTYH1 tweety homolog 1 Drosophila. The results are expressed as the mean ± SEM. * p < 0.05, ** p < 0.01 *** p <   0.01, *** p < 0.001, **** p < 0.0001, NC no statistically significant change