Fig. 4

Recovery of baseline expression of IL-25 mRNA after healing of the primary infection reverted the resistance against challenge infection together with a Th2 response. A Worm recovery of a primary infection in naïve mice and in that of a challenge infection in mice in which the basal levels of mRNA expression were recovered after the cure of a primary infection. B Expression of cytokine mRNA in the intestinal tissue of both groups of mice at 2 weeks after the primary and secondary infection (wppi and wpsi, respectively). The RQ of cytokine genes are shown after normalization with β-actin and standardization of the relative amount against the day 0 sample. Vertical bars represent the SD. Lowercase letters (a, b) above bars indicate either significant differences with respect to naïve mice controls (a) or significant differences between groups (b), at p  < 0.05