Protein regulation strategies of the mouse spleen in response to Babesia microti infection

Parasites & Vectors

Table 1 Immune-related proteins, iron metabolism-related proteins and growth and development-related proteins in the spleen tissues of mice infected with Babesia microti

Protein name	Accession	Description	5 days	8 days	11 days	19 days
CTSD	P18242	Cathepsin D	↓	↓	↑	↑
IFI44	Q8BV66	Interferon-induced protein 44	↑	↑	–	–
ILF2	Q3UXI9	Interleukin-2 enhancer binding factor 2	↓	↓	↓	–
ILF3	A0A1L1STE4	Interleukin enhancer-binding factor 3	↓	↓	↓	–
STAT5A^a	P42230	Signal transducer and activator of transcription 5A	–	↑	–	–
Lactoferrin	B8YJF9	Lactoferrin	↓	↓	↓	↓
Serotransferrin	Q921I1	Serotransferrin	↓	–	↑	–
TfR1	Q542D9	Transferrin receptor protein 1	↑	↑	↑	↑
GCLC	P97494	Glutamate-cysteine ligase	↑	↑	↑	↑
GCLM	O09172	Glutamate-cysteine ligase	–	–	↑	–
PKC-δ^a	P28867	Protein kinase C-δ	–	↓	↓	–
MAPK1^a	P63085	Mitogen-activated protein kinase 1	–	–	↓	–
MAPK3^a	D3Z3G6	Mitogen-activated protein kinase 3	–	–	↓	–
Grb2	Q60631	Growth factor receptor-bound protein 2	↓	↓	↓	–
PAK2	Q8CIN4	P21-activated kinase 2	–	↓	↓	–

ISSN: 1756-3305