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Table 1 Anti-Trichomonas vaginalis activity and cytoxicity effects of furanyl N-acylhydrazone (PFUR) derivatives 4a and 4b

From: Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: in vitro and in silico analyses

Compound

Trichomonas vaginalis

CHO-K1 cells

MIC

IC50 ± SEa

CC50

SI

PFUR 4a

6.25

1.69 ± 0.208

> 12.5

> 7.4

PFUR 4b

6.25

1.98 ± 0.121

> 2.5

> 6.3

  1. aStandard error (SE) as calculated by GraphPad Prism 7.03 software
  2. Notes: All results are expressed in μM, except for SI values. Trophozoites and cells were exposed to PFUR 4a and 4b for 24h for all in vitro assays
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Parasites & Vectors

ISSN: 1756-3305

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