Efficacy of a novel oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against natural flea and tick infestations on dogs presented as veterinary patients in Europe

Table 5 Efficacy of a single oral dose of Simparica Trio™ and afoxolaner+ milbemycin oxime against natural tick infestations across all species on dogs presented as veterinary patients in Europe

Study day	Treatment group	n	Live tick counts		% Efficacy
Study day	Treatment group	n	Range	Arithmetic mean	% Efficacy
− 1 to 0	Simparica Trio™	126	3–191	8.4	–
− 1 to 0	Afoxolaner + Milbemycin oxime	64	3–233	9.0	–
7 ± 2	Simparica Trio™	126	0–29	0.5	96.6
7 ± 2	Afoxolaner + Milbemycin oxime	64	0–13	0.6	94.4
14 ± 2	Simparica Trio™	126	0–15	0.4	94.8
14 ± 2	Afoxolaner + Milbemycin oxime	64	0–10	0.3	97.6
21 ± 2	Simparica Trio™	126	0–5	0.1	98.1
21 ± 2	Afoxolaner + Milbemycin oxime	64	0–2	0.1	97.8
30 ± 4	Simparica Trio™	126	0–4	0.1	98.6
30 ± 4	Afoxolaner + Milbemycin oxime	64	0–8	0.2	99.4

ISSN: 1756-3305