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Table 3 Adult Angiostrongylus vasorum worm counts in Studies 2 and 3: percent efficacy and statistical comparisons to placebo

From: Efficacy of orally administered combination of moxidectin, sarolaner and pyrantel (Simparica Trio™) for the prevention of experimental Angiostrongylus vasorum infection in dogs

StudyGroupaGeometric mean worm count% EfficacyTest statistic
Study 2Placebo54.4
Simparica Trio™3.394.0t(8.83) = 5.95,
P = 0.0002
Study 3Placebo94.8
Simparica Trio™6.892.9t(7.71) = 6.83,
P = 0.0002
  1. aThe Simparica Trio™-treated dogs received 24 µg/kg moxidectin, 1.2 mg/kg sarolaner and 5 mg/kg pyrantel