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Table 3 Adult Angiostrongylus vasorum worm counts in Studies 2 and 3: percent efficacy and statistical comparisons to placebo

From: Efficacy of orally administered combination of moxidectin, sarolaner and pyrantel (Simparica Trio™) for the prevention of experimental Angiostrongylus vasorum infection in dogs

Study

Groupa

Geometric mean worm count

% Efficacy

Test statistic

Study 2

Placebo

54.4

Simparica Trio™

3.3

94.0

t(8.83) = 5.95,

P = 0.0002

Study 3

Placebo

94.8

Simparica Trio™

6.8

92.9

t(7.71) = 6.83,

P = 0.0002

  1. aThe Simparica Trio™-treated dogs received 24 µg/kg moxidectin, 1.2 mg/kg sarolaner and 5 mg/kg pyrantel