Fig. 4

Prediction of regulatory elements in the 3′ untranslated regions (UTR) based on gene co-expression modules. a Predicted motifs for the gene modules are shown. Columns represent gene modules, while rows represent the predicted motifs with consensus sequence on the right side. Over-representation of a motif for a given gene module is indicated by yellow color with significant over-representation highlighted by red frames. Blue color map and frames indicate under-representation. b Motif pairs co-occurring in the 3′ UTR are shown in the heatmap where each row and each column correspond to a predicted motif. Light colors indicate the presence of another motif within the same 3′ UTR while dark colors indicate that the motifs are absent in the same 3′ UTR. “+” indicates significant spatial co-localization between pairs of motifs