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Table 2 Parasitological parameters, lung pathology and preventive drug efficacy against larvae excretion and (pre-)adult of Aelurostrongylus abstrusus

From: Efficacy of Bravecto® Plus spot-on solution for cats (280 mg/ml fluralaner and 14 mg/ml moxidectin) for the prevention of aelurostrongylosis in experimentally infected cats

Group Animal ID First day of L1 excretion (dpi) Max. L1 count/day in 5 g faeces GM of max. L1 count/day Efficacy (%) Lung pathology score (Pre-)adult worm count GM of adult worms Preventive efficacy (%)
1 (treated 12 weeks prior to infection) 0801 n.a. 0 1.10 99.99 1 0 0.09 99.66
1054 39 5 0 0
2936 n.a. 0 1 0
3881 37 1 0 0
5300 n.a. 0 1 1
6615 n.a. 0 0 0
8860 39 31 1 0
9657 n.a. 0 0 0
2
(treated 8 weeks prior to infection)
0370 n.a. 0 1.19 99.99 0 0 0.00 100
3599 36 1 0 0
5820 n.a. 0 2 0
6242 37 25 1 0
6554 n.a. 0 0 0
7273 42 9 0 0
7707 n.a. 0 1 0
8219 n.a. 0 0 0
3
(treated 4 weeks prior to infection)
0862 n.a. 0 0.53 99.98 0 0 0.00 100
1160 n.a. 0 0 0
1291 n.a. 0 0 0
3550 41 1 1 0
6179 44 9 0 0
6676 n.a. 0 0 0
9914 n.a. 0 1 0
4
(untreated control)
1151 33 45,900 7574.29 99.99 3 23 26.57 n.a.
1465 36 7400 3 36
1509 40 54 4 10
1588 38 1200 3 15
6407 33 43,100 4 64
6646 33 45,300 3 56
9013 36 11,300 3 23
9335 32 21,900 3 23
  1. dpi = day post infection, max. = maximum, GM = geometric mean, n.a. = not applicable