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Table 3 Analysis of calmodulin (CaM) and Ca2+/calmodulin-dependent protein kinase II (CaMKII) protein levels in E. multilocularis-infected mice after oral administration of Vepm for 4 months by enzyme-linked immunosorbent assay

From: Anti-echinococcal effect of verapamil involving the regulation of the calcium/calmodulin-dependent protein kinase II response in vitro and in a murine infection model

Index Sample Uninfected group Infected groupa Vepm groupb
CaM (μg/ml) Serum 13.81 ± 1.65 22.25 ± 5.55* 8.13 ± 1.26*
Liver 3.42 ± 0.27 6.06 ± 1.83* 1.60 ± 0.68*
Cysts NA 2.36 ± 0.87 1.68 ± 0.10
CaMKII (ng/ml) Serum 5.88 ± 0.99 22.87 ± 4.23* 5.13 ± 1.74*
Liver 2.00 ± 0.61 4.25 ± 1.84* 1.97 ± 0.56*
Cysts NA 2.65 ± 1.24 1.79 ± 0.36
  1. *P < 0.05
  2. aInfected group vs. the uninfected group
  3. bVepm group vs. the infected group