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Table 2 Average prevalences of moderate- and high-intensity infections in women of reproductive age

From: Deworming women of reproductive age during adolescence and pregnancy: what is the impact on morbidity from soil-transmitted helminths infection?

Modela Age period (years) SB only, mean (95% credible interval) SB + WRA, mean (95% credible interval) % Reduction, mean (95% credible interval)b P value
ICL 15–50 0.0216 (0.0142–0.0328) 4.81 × 10−3 (2.35 × 10−3–8.57 × 10−3) 77.8 (59.2–91.9) < 2.2 × 10−16
ICL 15–19 0.101 (0.06–0.141) 0.0173 (3.33 × 10-3–0.03) 83.5 (66.7–95.9) < 2.2 × 10−16
ICL 20–50 8.828 × 10−3 (3.88 × 10−3–0.0127) 2.73 × 10−3 (5.54 × 10−4–5.57 × 10−3) 61.5 (− 22.6 to 100) < 2.2 × 10−16
EMC 15–50 5.06 (4.54–5.46) 3.90 (3.47–4.26) 23.0 (20.1–26.0) < 2.2 × 10−16
EMC 15–19s 4.42 (3.93–4.85) 2.00 (1.70–2.35) 55.2 (50.6–60.3) < 2.2 × 10−16
EMC 20–50 5.16 (4.66–5.59) 4.21 (3.78–4.59) 18.3 (15.0–21.7) < 2.2 × 10−16
  1. Values in table are presented as the mean prevalence (%)
  2. aModerate baseline prevalence (20–50%) and annual SB treatment. The FoI inputted into the cohort model was extracted from the ICL and EMC fully stochastic individual-based models with annual ongoing SB treatment, i.e. FoI decreased over time. In the ICL model prevalences of moderate- and high-intensity infections (M&HI) infections in WRA are well below 1%. Therefore, the reduction in the prevalence of M&HI infections in absolute numbers is negligible and the uncertainty large
  3. bThe relative reduction is only calculated from time points where the prevalence of M&HI infections in simulations with the old treatment strategy (SB only) is > 0. All time points were used in the statistical comparison.