Table 3 Synergist drugs combined with ivermectin

Voriconazole

 Control

8.5 (8.0–9.1)

21.9

 Ivermectin

8.0 (7.5–8.5)

35.0

 IVM + VOR A

3667

5.4 (4.9–5.9)

59.8

 IVM + VOR B

2750

5.7 (5.3–6.0)

44.9

 IVM + VOR C

1833

7.6 (7.0–8.1)

42.2

 IVM + VOR D

916

7.4 (6.9–7.8)

34.7

Ritonavir

 Control

8.0 (7.5–8.4)

18.3

 Ivermectin

8.2 (7.7–8.8)

30.3

 IVM + RIF A

11,000

6.8 (6.1–7.5)

53.7

 IVM + RIF B

8250

6.6 (5.8–7.4)

51.8

 IVM + RIF C

5500

6.7 (6.1–7.3)

55.2

 IVM + RIF D

2750

7.3 (6.7–8.0)

42.3

Cobicistat

 Control

7.1 (6.8–7.5)

18.5

 Ivermectin

7.8 (7.1–8.4)

45.6

 IVM + COB A

990

8.6 (8.1–9.1)

23.6

 IVM + COB B

742

8.2 (7.8–8.7)

29.6

 IVM + COB C

495

7.5 (6.9–8.1)

39.0

 IVM + COB D

247

8.1 (7.6–8.6)

30.8

Elacridar

 Control

9.5 (9.3–9.8)

12.2

 Ivermectin

7.1 (6.5–7.6)

54.6

 IVM + ELA A

160

6.9 (6.4–7.4)

62.3

 IVM + ELA B

120

7.3 (6.8–7.8)

49.6

 IVM + ELA C

80

6.5 (6.1–7.0)

51.4

 IVM + ELA D

40

7.0 (6.5–7.4)

56.1

Cyclosporine A

 Control

9.0 (8.3–9.6)

15.6

 Ivermectin

9.0 (8.5–9.6)

21.8

 IVM + CYC A

1802

7.8 (6.8–8.8)

34.7

 IVM + CYC B

1351

7.7 (6.8–8.6)

38.1

 IVM + CYC C

901

7.7 (7.0–8.4)

20.9

 IVM + CYC D

450

8.5 (7.9–9.2)

33.3

Rifampicin

 Control

7.2 (6.6–7.7)

39.1

 Ivermectin

6.7 (6.0–7.5)

53.4

 IVM + RIF A

7000

6.9 (6.2–7.6)

49.5

 IVM + RIF B

5250

6.4 (5.6–7.1)

61.3

 IVM + RIF C

3500

8.2 (7.6–8.9)

31.5

 IVM + RIF D

1750

6.4 (5.8–7–0)

66.3