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Table 1 Non-synonymous mutations identified in the genomes of Zika virus after six passages in cell culture

From: Infection, dissemination, and transmission efficiencies of Zika virus in Aedes aegypti after serial passage in mosquito or mammalian cell lines or alternating passage in both cell types

Virus passage history Nucleotide position Codon sequencea Amino acid position Amino acid
ZIKV-I 256 ATT C 50 Ile
ZIKV-6C ATT Ile
ZIKV-6V ACT Thr
ZIKV-6A ACT Thr
ZIKV-I 869 AAA prM 132 Lys
ZIKV-6C AAC Asn
ZIKV-6V AAA Lys
ZIKV-6A AAA Lys
ZIKV-I 2925 GAA NS1 146 Glu
ZIKV-6C AAA Lys
ZIKV-6V GAA Glu
ZIKV-6A GAA Glu
ZIKV-I 3895 GCG NS2A 117 Ala
ZIKV-6C GCG Ala
ZIKV-6V GTG Val
ZIKV-6A GTG Val
  1. aNucleotide substitutions are bolded