Fig. 4
From: Serum proteomic profiling in patients with advanced Schistosoma japonicum-induced hepatic fibrosis
Bioinformatics analysis of differentially expressed proteins in the serum samples from SHF-F2 and SHF-F4 patients. a Volcano plot representing the changes in protein abundance (groups C [SFH-F4 patients] vs B [SFH-F2 patients]). A total of 214 dysregulated proteins with fold change ≥ ±1.5 and P values < 0.05 were identified. b Hierarchical clustering of the 214 dysregulated proteins (groups C vs B). c GO analysis of 214 dysregulated proteins (groups C vs B). The abscissa repressents enriched GO function classifications, which are divided into three major ctegories: biological process (BP), molecular function (MF) and cellular component (CC). d The 214 dysregulated proteins (groups C vs B) were classified in terms of their subcellular localizations