Table 3 Effectiveness of a single oral dose of Credelio Plus against natural nematode infections in dogs presenting to European veterinary clinics
NNematode species | Samplea | Treatment groupb | Number of dogs | Egg count per gram faeces | |||
|---|---|---|---|---|---|---|---|
Geometric Mean (GM) | GM % reduction | Number of dogs with zero eggs (%) | Effectiveness P-valuec | ||||
All nematode species | Pre-treatment | Credelio Plus Afoxolaner + MO | 278 117 | 13.2 11.2 | – – | – – | – – |
Post-treatment | Credelio Plus Afoxolaner + MO | 278 117 | 0.3 0.3 | 97.6 97.0 | 245 (88.2%) 99 (84.6%) | < 0.0001 (t524 = 24.33) < 0.0001 (t524 = 14.65) | |
Toxocara canis | Pre-treatment | Credelio Plus Afoxolaner + MO | 54 19 | 16.4 8.0 | – – | – – | – – |
Post-treatment | Credelio Plus Afoxolaner + MO | 54 19 | 0.5 0.4 | 97.2 95.3 | 48 (88.9%) 16 (84.2%) | < 0.0001 (t79.3 = 4.36) < 0.0001 (t79.3 = 9.70) | |
Ancylostoma caninum | Pre-treatment | Credelio Plus Afoxolaner + MO | 109 42 | 11.2 9.9 | – – | – – | – – |
Post-treatment | Credelio Plus Afoxolaner + MO | 109 42 | 0.2 0.5 | 98.1 95.3 | 100 (91.7%) 35 (83.3%) | < 0.0001 (t185 = 9.28) < 0.0001 (t185 = 17.19) | |
Trichuris vulpis | Pre-treatment | Credelio Plus Afoxolaner + MO | 176 80 | 9.8 9.7 | – – | – – | – – |
Post-treatment | Credelio Plus Afoxolaner + MO | 176 80 | 0.2 0.1 | 97.8 98.5 | 156 (88.6%) 73 (91.2%) | < 0.0001 (t340 = 12.79) < 0.0001 (t340 = 18.57) | |