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Table 1 PBMC transcripts with a statistically significant change in expression between ivermectin- and placebo-treated samples 4 h after administration

From: Lack of detectable short-term effects of a single dose of ivermectin on the human immune system

Transcript

Product

Log2 fold change

p-value

BY.p.value

Gene sets

PTAFR

Platelet-activating factor receptor

−1.04

1.01E−5

0.0349

Interferon signalling

PROK2

Prokineticin 2

−2.96

2.75E−5

0.0403

Angiogenesis

HDAC5

Histone deacetylase 5

−0.65

3.48E−5

0.0403

Growth factor signalling

  1. The Benjamini-Yekutieli (BY) p value is that obtained after correcting for the false discovery rate [35]