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Table 1 Mean weights (mg) (95% confidence interval) of Amblyomma americanum ticks removed from lotilaner-treated and from sham-treated control dogs at 2, 4, 8 and 24 h post attachment

From: Early onset of pre-lethal effects of lotilaner (Credelio®) on Amblyomma americanum ticks on experimentally infested dogs

Time post attachment (h)

Males

Females

Treated

Control

Z-value

P-value

Treated

Control

Z-value

P-value

2

2.45 (2.18‒2.71)

2.29 (2.13‒2.45)

1.00

0.3222

4.41 (3.96‒4.86)

4.30 (3.43‒5.17)

0.04

0.9650

4

2.32 (2.10‒2.54)

2.64 (2.35‒2.92)

1.55

0.1214

3.92 (3.39‒4.44)

4.08 (3.78‒4.39)

0.54

0.5865

8

2.17 (1.86‒2.48)

2.44 (2.22‒2.67)

1.02

0.3062

3.92 (3.43‒4.42)

4.44 (2.18‒2.71)

1.47

0.1419

24

1.69 (1.47‒1.92)

2.66 (2.32‒3.01)

3.71

0.0002

2.72 (2.29‒3.16)

4.67 (4.13‒5.22)

3.97

< 0.0001