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Fig. 3 | Parasites & Vectors

Fig. 3

From: Establishment and validation of a guinea pig model for human congenital toxoplasmosis

Fig. 3

Impact of the infection duration on the dam survival rate. Kaplan-Meier survival rate of dams of the control and different infection groups. Animals were infected with 10 (a), 100 (b) and 500 (c) sporulated oocysts on gestation day 15 (purple solid line), 30 (red solid line) and 48 (green solid line). Animals of the control group (black dashed line) were administered PBS. The end of the trial for a given dam was defined by death, euthanasia due to a critical health score or abortion or by euthanasia on the day of birth. Merged data of all infection days, irrespective of the day of gestation (a–c) are shown in (d). Statistically significant differences are as follows: (c) P < 0.05, comparing control and 30; P < 0.05, comparing control and 48; P < 0.05, comparing 15 and 48; P < 0.05, comparing 30 and 48; (d) P < 0.5, comparing 15 and 48

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