Fig. 3
From: Evaluation of two Plasmodium vivax sexual stage antigens as transmission-blocking vaccine candidates
Evaluation of transmission-reducing activities of mouse antisera against PvPH, PvSOP26, and GST with Plasmodium vivax clinical isolates. A direct membrane feeding assay was performed for three P. vivax isolates (#1, #2 and #3, respectively, on the x-axis) with reconstituted blood consisting of mouse antisera mixed with heat-inactivated AB-positive blood type healthy human serum at 1:1. The numbers of oocysts in individual mosquito midguts are shown in the scatter dot plot. The long horizontal bar designates the median number of oocysts, while the two short horizontal bars indicate interquartile ranges in each group. * and *** indicate significant differences at P < 0.05 and P < 0.001, respectively (Mann–Whitney U-test). #2 control vs PvSOP26: U(19) = 40.5, Z = − 4.32, P < 0.0001; #3 control vs PvSOP26: U(19) = 13, Z = − 5.06, P = 0.014