Risk of dementia in patients with toxoplasmosis: a nationwide, population-based cohort study in Taiwan

Parasites & Vectors

Table 1 Characteristics of study population at the baseline

Toxoplasmosis	With		Without		P-value*
Variables	n	%	n	%	P-value*
Total	200	25.00	600	75.00
Gender					0.999
Male	87	43.50	261	43.50
Female	113	56.50	339	56.50
Age (years)	62.11 ± 8.88		63.18 ± 8.71		0.135
Age groups (years)					0.999
50–64	131	65.50	393	65.50
≧65	69	34.50	207	34.50
Insurance premium (NT$)					< 0.001
< 18,000	143	71.50	593	98.83
18,000–34,999	48	24.00	7	1.17
≧35,000	9	4.50	0	0
Diabetes mellitus					0.014
Without	179	89.50	493	82.17
With	21	10.50	107	17.83
Hypertension					0.482
Without	155	77.50	479	79.83
With	45	22.50	121	20.17
Hyperlipidemia					0.357
Without	196	98.00	578	96.33
With	4	2.00	22	3.67
Coronary artery disease					0.885
Without	183	91.50	547	91.17
With	17	8.50	53	8.83
Obesity					-
Without	200	100	600	100
With	0	0	0	0
HIV					< 0.001
Without	196	98.00	596	99.33
With	4	2.00	4	0.67
Immune deficiency					< 0.001
Without	190	95.00	589	98.17
With	10	5.00	11	1.83
CCI_R	0.76 ± 1.84		0.69 ± 1.48		0.596
Location					< 0.001
Northern Taiwan	68	34.00	244	40.67
Central Taiwan	96	48.00	162	27.00
Southern Taiwan	26	13.00	170	28.33
Eastern Taiwan	8	4.00	22	3.67
Outlying islands	2	1.00	2	0.33
Urbanization level					0.003
1 (highest)	53	26.50	208	34.67
2	96	48.00	260	43.33
3	15	7.50	39	6.50
4 (lowest)	36	18.00	93	15.50
Level of care					0.002
Hospital center	81	40.50	220	36.67
Regional hospital	75	37.50	172	28.67
Local hospital	44	22.00	208	34.67
Department of visits in study period
Infection	1.12 ± 1.30		0.85 ± 1.08		0.004
Neurology	2.54 ± 2.69		2.03 ± 2.51		0.015
Psychiatry	3.01 ± 3.47		2.75 ± 2.83		0.289

*Chi-square/Fisher exact test for categorical variables and t-test for continuous variables, CCI_R Charlson Comorbidity Index, dementia and HIV removed

ISSN: 1756-3305