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Table 1 Serum biochemical findings and blood cell analysis in BALB/c mice treated with thiacloprid for 6 weeks (n = 6)

From: In vitro and in vivo efficacy of thiacloprid against Echinococcus multilocularis

Balb/c mice

Control

Thia 15

Thia 30

Alanine aminotransferase (U/L)

65.67 ± 6.53

66.00 ± 5.33

67.50 ± 5.01

Aspartate aminotransferase (U/L)

198.20 ± 28.15

164.70 ± 36.71

180.50 ± 45.71

Alkaline phosphatase (U/L)

84.33 ± 4.46

57.67 ± 5.43*

58.50 ± 7.82*

Total protein (g/L)

63.30 ± 2.41

65.90 ± 4.76

65.82 ± 4.39

Globulin (g/L)

34.80 ± 2.83

36.67 ± 4.71

37.77 ± 4.81

Albumin (g/L)

28.50 ± 1.57

28.95 ± 2.35

29.72 ± 1.49

Total bilirubin (μM/L)

0.66 ± 0.22

0.60 ± 0.10

0.59 ± 0.16

Direct bilirubin (μM/L)

1.10 ± 0.05

0.13 ± 0.05

0.19 ± 0.16

Indirect bilirubin (μM/L)

0.51 ± 0.25

0.44 ± 0.17

0.42 ± 0.19

Blood urea nitrogen (mmol/L)

9.31 ± 1.02

7.23 ± 1.87*

7.15 ± 0.47*

Creatinine (μM/L)

16.07 ± 3.43

16.08 ± 1.87

15.18 ± 2.44

RBC (1012/L)

10.97 ± 1.26

11.39 ± 1.48

9.58 ± 0.82

Hemoglobin (g/L)

214.30 ± 11.78

203.00 ± 11.15

206.0 ± 9.93

WBC (109/L)

12.92 ± 0.18

11.69 ± 1.30

12.72 ± 1.75

PLT (109/L)

673.00 ± 120.80

613.70 ± 145.00

670.80 ± 150.20

  1. *P < 0.05 vs. control