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Fig. 4 | Parasites & Vectors

Fig. 4

From: Schistosoma japonicum peptide SJMHE1 inhibits acute and chronic colitis induced by dextran sulfate sodium in mice

Fig. 4

SJMHE1 treatment modulates Th1/Th2/Th17/Treg cell distribution in the MLNs of mice with DSS-induced acute colitis. On day 10, the mice were killed, and the MLNs from each mouse were tested for Th1/Th2/Th17/Treg subsets through flow cytometry. ad Proportion of Th1/Th2/Th17/Treg subsets in each treatment group: a CD4+IFN-γ+ Th1 cells, b CD4+IL-4+ Th2 cells, c CD4+IL-17+ Th17 cells, d CD4+CD25+Foxp3+ Treg cells. Data are representative of the experiments. eh Percentages of Th1/Th2/Th17/Treg cells in each treatment group: e CD4+IFN-γ+ Th1 cells, f CD4+IL-4+ Th2 cells, g CD4+IL-17+ Th17 cells, h CD4+CD25+Foxp3+ Treg cells. Results are presented as mean ± SEM of 18 mice from three independent experiments. Asterisks indicate significant difference at: *P < 0.05, **P < 0.01, ***P < 0.001

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