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Table 3 Summary of the most relevant results regarding clinical signs and serological results in naturally infected bulls (chronically and subclinically infected bulls)

From: Changes in serum biomarkers of inflammation in bovine besnoitiosis

Group

No. animals

Systemic clinical signs/ lesions

Lesions in testicles

Parasite DNA detection

Serology

Macroscopic lesions

Microscopic findings

Humoral

IgM

IgG

WB

IgG avidity

Chronic infection

9

Folds and hyperkeratosis skin of perineum, carpus and tarsus, presence of cysts in scleral conjunctiva

Folds and hyperkeratosis in scrotum, skin of perineum, carpus and tarsus

Inflammatory infiltrate, skin lesions and tissue cysts (average diameter of tissue cysts = 191.0 μm)

Yes

Pos

Pos

Pos

High

Subclinical infection

34

No clinical signs or lesions

No lesions

Samples not available

nd

nd

Pos

Pos

nda

Non-infected bulls

40

No clinical signs or lesions

No lesions

No lesions

nd

Neg

Neg

Neg

nd

  1. Pos positive, Neg negative, nd not determined. aBulls with subclinical infection were IgG-seropositive in several consecutive samplings