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Table 2 Schedule of the clinical examinations and adverse event observation performed in the two efficacy studies

From: Efficacy of a spot-on combination containing 10% w/v imidacloprid and 1% w/v moxidectin for the treatment of troglostrongylosis in experimentally infected cats

Assessments

Study 1

Study 2

Clinical assessment (health assessment around inoculation and/or treatment time points)

SD 28; SD 29; SD 56; SD 57

SD 0; SD 26; SD 27; SD 54; SD 55

Physical examination (complete clinical examination including auscultation)

SD −7a; SD −1

SD −9; SD −1; SD 23; SD 51; SD 63

Respiratory assessment

SD −1; SD 7; SD 14; SD 21; SD 27; SD 35; SD 41; SD 49; SD 55; SD 63; SD 69–72

NA

Adverse event observation

From SD 28 to SD 69/72

From SD 26 to SD 64/65

  1. NA not applicable, SD study day
  2. aDue to the extended acclimation period SD −7 activities took place 14 days before inoculation