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Table 1 Results from counts of Demodex canis mites obtained from deep skin scrapings

From: Fluralaner 5.46% (w/w) flavored chewable tablet (Bravecto® 1-Month) is effective for treatment of canine generalized demodicosis

   Fluralaner tablets Topical imidacloprid-moxidectin
Day −2  Arithmetic mean (SD) 639.9 (589.9) 608.5 (459.5)
   Median 507.5 459.0
   Range 19‒1764 90‒1314
   Geometric mean 347.5 432.3
Day 28  Arithmetic mean (SD) 2.0 (2.8) 63.9 (118.3)
   Median 0.0 17.0
   Range 0‒6 0–351
   P-value (vs day −2)  < 0.0005*  < 0.0001*
   Test statistics t(19) = 4.18 t(21) = 5.05
   Geometric mean 1.0 17.2
Day 56  Arithmetic mean (SD) 0 (0.0) 34.1 (70.3)
   Median 0.0 11.0
   Range 0‒0 0‒207
   P-value (vs day −2) 0.0007*  < 0.0001*
   Test statistics t(19) = 4.05 t(21) = 5.33
   Geometric mean 0.0 8.5
Day 84  Arithmetic mean (SD) 0 (0.0) 15.0 (22.8)
   Median 0.0 3.5
   Range 0‒0 0‒65
   P-value (vs day −2) 0.0007*  < 0.0001*
   Test statistics t(19) =4.05 t(21) = 5.51
   Geometric mean 0.0 5.1
  1. SD standard deviation
  2. *Statistically significant