Table 4 Distribution of the parasitic load detected using H&E staining, IHC and qPCR, and the association with severity of dermal inflammation
Severity of dermal inflammation (N) | Parasite load | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
H&E staininga | IHCa | qPCRa | ||||||||||||
Negative (â) | Suspect (+/â) | Mild (+) | Moderate (++) | Intense (+++) | Negative (â) | Suspect (+/â) | Mild (+) | Moderate (++) | Intense (+++) | Negative (â) | Low (+) | Moderate (++) | Intense (+++) | |
Mild (+) (6) | 5 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 1 | 2 | 3 | 0 | 1 |
Moderate (++) (13) | 7 | 2 | 1 | 1 | 2 | 7 | 1 | 1 | 3 | 1 | 3 | 4 | 2 | 4 |
Severe (+++) (11) | 5 | 3 | 0 | 2 | 1 | 3 | 0 | 6 | 0 | 2 | 4 | 0 | 3 | 4 |
Ï2 (p) | 5.7 (0.77) | 15.64 (0.029)* | 7.34 (0.29) | |||||||||||
r (p) | 0.18 (0.33) | 0.26 (0.099) | 0.13 (0.41) | |||||||||||