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Fig. 2 | Parasites & Vectors

Fig. 2

From: Evaluations of candidate markers of dihydroartemisinin-piperaquine resistance in Plasmodium falciparum isolates from the China–Myanmar, Thailand–Myanmar, and Thailand–Cambodia borders

Fig. 2

a Pie chart of CQ-, ART-, and PPQ-resistant haplotypes and their relationships. CVIET/SL, CQ-resistant haplotype; CVIET/SL/F446I, major ART-resistant type in CM; CVIET/SL/C580Y, major ART-resistant type in TC and TM; CVIET/SL/F446I/H97L, possible PPQ-resistant type in CM; CVIET/SL/C580Y/I218F, CVIET/SL/C580Y/H97L, possible PPQ-resistant type in TC and TM. b Haplotype network based on 14 single-nucleotide polymorphisms (SNPs) of pfcrt and 15 SNPs of pfkelch13 in this study. Each observed haplotype is indicated by a filled circle, sized according to its frequency and colored according to the border region represented. Haplotype relationships are indicated by lines; mutational steps between haplotypes are represented by the number of lines. CM China–Myanmar border, TM Thailand–Myanmar border, TC Thailand–Cambodia border, R resistant, W wild-type

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Parasites & Vectors

ISSN: 1756-3305

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