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Table 2 Dynamics of infection in animals experimentally inoculated with spirochetemic blood collected from humans with soft tick-borne relapsing fever in Colombia [68]

From: Historical overview and update on relapsing fever group Borrelia in Latin America

Animal (n)a

Collection of the inoculated blood sample (febrile/afebrile period)

Days to first observation of spirochetes in bloodb

Consecutive days of visible spirochetes in bloodb

Relapsing occurrence (no. of animals with relapsing)

Wild rat, undetermined species (2)

Febrile

2

3

No relapse

Young guinea pig (3)

Febrile

2–4

1

No relapse

Young rabbit (1)

Febrile

1

1

No relapse

White rat (6)

Febrile

1

3

Yes (2)d

White rat (2)

Afebrilec

4

1–4

Yes (2)e

  1. aAll animals were inoculated subcutaneously or intraperitoneally with samples of spirochetes-positive human blood (0.5–1.0 mL)
  2. bBy thick blood smear
  3. cBetween first and second febrile episode
  4. dAt 4 days after the last spirochete detection
  5. eAt 2–5 days after the last spirochete detection