Fig. 3

Linear organization of Aedes aegypti FAS genes showing functional domains. (a) Schematic shows linear organization of seven catalytic and three noncatalytic domains of mammalian FAS annotated by Maier et al. [1]. Seven catalytic domains are shown in big squares, and three non-catalytic domains are shown in smaller squares. KS β-ketoacyl synthase; LD linker; MAT malonyl-acetyl transferase; DH dehydratase; ΨME pseudo-methyltransferase; ΨKR pseudo β-ketoacyl synthase; ER enoyl reductase; KR β-ketoacyl synthase; ACP acyl carrier protein and TE thioesterase. b Schematics show conserved domains or motifs of FAS genes and their organization annotated using Pfam 31.0 software. ketoacyl_synt β-ketoacyl synthase; ketoacyl_synt_C β-ketoacyl-acyl carrier protein synthase; ketoacyl_assoc ketoacyl-synthase C-terminal extension; acyl_transf_1 acyl transferase domain; PS-DH polyketide synthase; methyltransf methyltransferase domain; ADH-zinc zinc binding dehydrogenase; KR β-ketoreductase domain; PP-binding phosphopantetheine attachment site; thioesterase thioesterase domain