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Fig. 5 | Parasites & Vectors

Fig. 5

From: Structural analysis of PpSP15 and PsSP9 sand fly salivary proteins designed with a self-cleavable linker as a live vaccine candidate against cutaneous leishmaniasis

Fig. 5

The outputs of the AlphaFold2 server for the selected vaccine candidate construct. The AlphaFold2 server provides 3D models from the amino acid sequences for the selected construct (PpSP15-T2A-PsSP9) as a whole and constituting proteins (PpSP15-T2A and PsSP9-His-tag) based on two confidence metrics: pLDDT, predicted Local Distance Difference Test a and PAE, Predicted Aligned Error b. Residues with pLDDT ≥ 70 are confident (lower values are detectable around the T2A linker). The lower PAE (around zero in blue) shows higher prediction quality

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Parasites & Vectors

ISSN: 1756-3305

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