Variables | No. of studies | Estimated prevalence | (95% CI) | P-value | Heterogeneity | Meta-regression | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
SS | Cases | Prev. (%) | Q-value | I2 (%) | Q-P | P-value | OR (95% CI) | ||||
Regions | |||||||||||
 C/Africa | 1 | 128 | 0 | 0.39 | 0.02, 5.89 | < 0.001 | 0.00 | 0.00 | 1.000 | < 0.001 | − 2.95 (− 6.31, 0.41) |
 E/Africa | 11 | 4017 | 843 | 21.01 | 11.61, 35.01 |  | 519.54 | 98.08 | < 0.001 |  | 1.25 (0.38, 2.12) |
 N/Africa | 20 | 3834 | 958 | 25.62 | 20.44, 31.58 |  | 233.59 | 91.87 | < 0.001 |  | 1.52 (0.73, 2.30) |
 S/Africa | 1 | 1063 | 10 | 0.94 | 0.51, 1.74 |  | 0.00 | 0.00 | 1.000 |  | − 2.06 (− 4.05, − 0.06) |
 W/Africa | 9 | 28,458 | 2608 | 6.53 | 3.12, 13.15 |  | 172.88 | 95.37 | < 0.001 |  | Reference |
MOD | |||||||||||
 ELISA | 3 | 619 | 140 | 23.58 | 12.76, 39.42 | < 0.001 | 29.55 | 93.23 | < 0.001 | 0.298 | 0.91 (− 0.61, 2.42) |
 Microscopy | 27 | 31,806 | 3482 | 18.44 | 11.86, 27.53 |  | 1785.75 | 98.54 | < 0.001 |  | 0.61 (− 0.24, 1.46) |
 PCR | 12 | 5075 | 797 | 13.18 | 8.36, 20.17 |  | 303.58 | 96.38 | < 0.001 |  | Reference |
Study period | |||||||||||
 1975–1990 | 15 | 3394 | 567 | 16.61 | 9.24, 28.06 | < 0.001 | 412.06 | 96.60 | < 0.001 | < 0.001 | − 2.31 (− 3.55, − 1.08) |
 1991–2006 | 9 | 1699 | 287 | 23.35 | 15.26, 34.00 |  | 86.84 | 90.79 | < 0.001 |  | 0.70 (0.08, 1.33) |
 2007–2021 | 18 | 32,407 | 3565 | 15.07 | 9.79, 22.49 |  | 1275.55 | 98.67 | < 0.001 |  | Reference |
Sample size | |||||||||||
 ≤ 200 | 25 | 2451 | 565 | 23.48 | 17.49, 30.76 | < 0.001 | 257.59 | 90.68 | < 0.001 | 0.137 | 0.41 (− 1.10, 1.92) |
 201–400 | 10 | 2782 | 515 | 11.72 | 5.17, 24.45 |  | 512.24 | 98.24 | < 0.001 |  | 0.74 (0.01, 1.47) |
 > 400 | 17 | 32,267 | 3339 | 10.44 | 5.30, 19.53 |  | 932.95 | 99.36 | < 0.001 |  |  |
Sex | |||||||||||
 Female | 4 | 868 | 350 | 35.79 | 25.35, 47.77 | 0.224 | 40.53 | 90.13 | < 0.001 | 0.855 | 0.07 (− 0.66, 0.79) |
 Male | 4 | 910 | 341 | 33.92 | 23.23, 46.56 |  | 49.44 | 91.91 | < 0.001 |  | Reference |
Dog type | |||||||||||
 Owned | 15 | 3351 | 506 | 15.92 | 10.89, 22.71 | < 0.001 | 229.88 | 93.91 | < 0.001 | 0.006 | − 0.77 (− 1.32, − 0.22) |
 Stray | 21 | 1672 | 491 | 29.65 | 23.22, 37.01 |  | 150.59 | 86.72 | < 0.001 |  | Reference |
 Overall | 42 | 37,500 | 4419 | 16.94 | 12.65, 22.32 |  | 2355.16 | 98.26 | < 0.001 |  |  |