Table 1 Heat shock proteins (HSPs) identified in Schistosoma mansoni and the corresponding Schistosoma japonicum and Schistosoma haematobium HSPs
| Â | S. mansoni | S. japonicum | S. haematobium | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
HSP family | Protein identifier | Proposed name | E-value | %ID | Protein identifier | Proposed name | E-value | %ID | Protein identifier | Proposed name | E-value | %ID |
HSP 10 | Smp_097380.1 | 10Â kDa HSP, mitochondrial-like | 5.6E-38 | 68 | No hit | No hit | No hit | No hit | No hit | No hit | No hit | No hit |
HSP 60 | Smp_008545.1 | 60Â kDa HSP, mitochondrial-like | 0 | 73.1 | Sjp_0082590 | 60Â kDa HSP, mitochondrial-like | 0 | 93.5 | MS3_0017475.1 | 60Â kDa HSP, mitochondrial-like | 0 | 97.8 |
HSP 40 | Smp_035200.1 | DnaJ homolog subfamily A member 1 isoform 1–like | 5.8E-100 | 56.5 | Sjp_0016830 | DnaJ homolog subfamily A member 1 isoform 1-like | 0 | 78.6 | MS3_0013770.1 | DnaJ homolog subfamily A member 1 isoform 1-like | 0 | 97.7 |
Smp_096010.2 | DnaJ (Hsp40) homolog, subfamily A, member 3-like | 5.6E-45 | 58.5 | Sjp_0043020 | DnaJ (Hsp40) homolog, subfamily A, member 3 -like | 2.0E-148 | 86.1 | MS3_0015757.1 | DnaJ (Hsp40) homolog, subfamily A, member 3 -like | 2.0E-109 | 88.1 | |
Smp_104730.1 | DnaJ homolog subfamily B member 13-like | 6.8E-64 | 52.5 | Sjp_0050750 | DnaJ homolog subfamily B member 13-like | 2.0E-113 | 87.4 | MS3_0016335.1 | DnaJ homolog subfamily B member 13-like | 0 | 96.8 | |
Smp_022330.1 | DnaJ homolog subfamily B member 8-like | 1.7E-27 | 70.3 | Sjp_0011040 | DnaJ homolog subfamily B member 2 isoform b-like | 9.3E-85 | 90.3 | MS3_0017548.1 | DnaJ homolog subfamily B member 8-like | 4.9E-137 | 97 | |
Smp_317860.1 | DnaJ homolog subfamily B member 8-like | 1.3E-27 | 70.3 | Sjp_0011040 | DnaJ homolog subfamily B member 2 isoform b-like | 2.2E-74 | 81.3 | MS3_0017548.1 | DnaJ homolog subfamily B member 8-like | 2.1E-120 | 86.9 | |
Smp_317870.1 | DnaJ homolog subfamily B member 8-like | 1.3E-27 | 70.3 | Sjp_0011040 | DnaJ homolog subfamily B member 2 isoform b-like | 2.1E-75 | 82.1 | MS3_0017548.1 | DnaJ homolog subfamily B member 8-like | 1.8E-121 | 87.4 | |
Smp_020920.1 (Smp_336770) | DnaJ homolog subfamily B member 4 isoform a-like | 1.3E-34 | 49.1 | Sjp_0094860 | DnaJ homolog subfamily B member 4 isoform c-like | 5.9E-116 | 88.4 | MS3_0016371.1 | DnaJ homolog subfamily B member 4 isoform a-like | 0 | 94 | |
Smp_136540.1 | DnaJ homolog subfamily B member 2 isoform a-like | 1.2E-26 | 60.6 | Sjp_0011040 | DnaJ homolog subfamily B member 2 isoform b-like | 7.2E-09 | 37.7 | MS3_0015969.1 | DnaJ homolog subfamily B member 2 isoform a-like | 6.6E-78 | 94.4 | |
Smp_078800.1 | DnaJ homolog subfamily B member 9 precursor-like | 4.0E-28 | 58 | Sjp_0009490 | DnaJ homolog subfamily B member 9 precursor-like | 1.7E-55 | 84.4 | MS3_0017753.1 | DnaJ homolog subfamily B member 9 precursor-like | 1.4E-34 | 89.6 | |
Smp_141080.1 | DnaJ homolog subfamily B member 11 precursor-like | 4.7E-88 | 64 | Sjp_0073420 | DnaJ homolog subfamily B member 11 precursor-like | 0 | 85.6 | MS3_0013749.1 | DnaJ homolog subfamily B member 11 precursor-like | 0 | 93.2 | |
Smp_132870.1 | DnaJ homolog subfamily B member 12 isoform 1 -like | 4.5E-30 | 47.5 | Sjp_0101050 | DnaJ homolog subfamily B member 12 isoform 1-like | 6.4E-78 | 79.9 | MS3_0018634.1 | DnaJ homolog subfamily B member 12 isoform 1-like | 2.2E-92 | 90.6 | |
Smp_043970.1 | DnaJ homolog subfamily C member 8-like | 3.0E-72 | 53.6 | Sjp_0014880 | DnaJ homolog subfamily C member 8-like | 8.2E-139 | 92.2 | MS3_0016818.1 | DnaJ homolog subfamily C member 8-like | 6.8E-100 | 97.7 | |
Smp_105960.1 | DnaJ homolog subfamily C member 2 isoform 3-like | 2.1E-29 | 56.3 | Sjp_0041520 | DnaJ homolog subfamily C member 2 isoform 3-like | 1.7E-104 | 77.8 | MS3_0013950.1 | DnaJ homolog subfamily C member 2 isoform 3-like | 1.5E-147 | 90.7 | |
Smp_049600.1 | DnaJ homolog subfamily C member 3 precursor-like | 1.4E-34 | 33.3 | Sjp_0073570 | DnaJ homolog subfamily C member 3 precursor-like | 0 | 88.6 | MS3_0019665.1 | DnaJ homolog subfamily C member 3 precursor-like | 0 | 96.1 | |
Smp_000850.1 | DnaJ homolog subfamily C member 5 -like | 2.3E-30 | 57.5 | Sjp_0031300 | DnaJ homolog subfamily C member 5-like | 3.1E-59 | 95.8 | MS3_0013749.1 | DnaJ homolog subfamily B member 11 precursor-like | 7.1E-19 | 50 | |
Smp_333510.1 (Smp_194080) | DnaJ homolog subfamily C member 5-like | 8.8E-24 | 55.3 | Sjp_0036360 | DnaJ homolog subfamily C member 5-like | 4.0E-41 | 94.4 | MS3_0016335.1 | DnaJ homolog subfamily B member 13-like | 2.7E-11 | 32.6 | |
Smp_047190.1 | Cyclin-G-associated kinase isoform 1-like | 3.4E-47 | 40.8 | Sjp_0067780 | Cyclin-G-associated kinase isoform X15-like | 3.0E-154 | 89.4 | MS3_0011786.1 | Cyclin-G-associated kinase isoform X20-like | 0 | 95 | |
Smp_138680.1 | DnaJ homolog subfamily C member 7 isoform 1-like | 5.1E-75 | 36.4 | Sjp_0012490 | DnaJ homolog subfamily C member 7 isoform 1-like | 0 | 83.9 | MS3_0012833.1 | DnaJ homolog subfamily C member 7 isoform 1-like | 0 | 96.3 | |
Smp_083450.1 | DnaJ homolog subfamily C member 9-like | 1.0E-21 | 43.6 | Sjp_0011820 | DnaJ homolog subfamily C member 9-like | 2.7E-106 | 82.6 | MS3_0020257.1 | DnaJ homolog subfamily C member 9-like | 5.6E-119 | 93.5 | |
Smp_146900.1 | DnaJ (Hsp40) homolog, subfamily C, member 11-like | 2.3E-18 | 32.3 | Sjp_0035710 | DnaJ (Hsp40) homolog, subfamily C, member 11-like | 8.1E-129 | 79.7 | MS3_0013061.1 | DnaJ (Hsp40) homolog, subfamily C, member 11-like | 0 | 94.8 | |
Smp_006690.3 | DnaJ homolog subfamily C member 17-like | 2.8E-17 | 43.3 | Sjp_0091520 | DnaJ homolog subfamily C member 17-like | 1.7E-43 | 76.5 | MS3_0013749.1 | DnaJ homolog subfamily B member 11 precursor-like | 1.9E-09 | 37.5 | |
Smp_346390.2 (Smp_175760) | DnaJ homolog subfamily C member 13 isoform 2 -like | 7.9E-88 | 52.1 | Sjp_0002640 | DnaJ homolog subfamily C member 13 isoform 2-like | 1.4E-165 | 88.2 | MS3_0018783.1 | DnaJ homolog subfamily C member 13 isoform 2-like | 0 | 97.9 | |
Smp_151650.1 | DnaJ homolog subfamily C member 15-like | 1.2E-29 | 72.2 | Sjp_0059500 | DnaJ homolog subfamily C member 15-like | 1.1E-52 | 84.0 | MS3_0018935.1 | DnaJ homolog subfamily C member 15-like | 3.5E-57 | 92 | |
Smp_341040.1 (Smp_065650) | DnaJ-like | 2.9E-09 | 45.3 | Sjp_0008430 | No hit | 7.0E-48 | 67.3 | MS3_0014878.1 | No hit | 4.5E-60 | 85.1 | |
Smp_172510.1 | DnaJ homolog subfamily C member 21 isoform 2-like | 8.4E-27 | 39.5 | Sjp_0072370 | DnaJ homolog subfamily C member 21 isoform 2-like | 1.7E-88 | 79.1 | MS3_0019394.1 | DnaJ homolog subfamily C member 21 isoform 2-like | 5.0E-147 | 94.7 | |
Smp_145670.1 | SEC63 protein-like | 3.6E-58 | 47.6 | Sjp_0075500 | SEC63 protein-like | 6.0E-163 | 89.8 | MS3_0018814.1 | SEC63 protein-like | 0 | 98.2 | |
Smp_136910.1 | DnaJ homolog subfamily C member 25 precursor-like | 9.7E-11 | 46.5 | Sjp_0003990 | DnaJ homolog subfamily C member 25 precursor-like | 9.6E-176 | 90.1 | MS3_0019269.1 | DnaJ homolog subfamily C member 25 precursor-like | 3.9E-177 | 96.2 | |
Smp_342140.1 (Smp_125170) | DnaJ homolog subfamily C member 27 isoform 2-like | 7.3E-47 | 53.5 | Sjp_0023950 | Ras-related protein Rab-10-like | 7.9E-21 | 30.9 | MS3_0015015.1 | DnaJ homolog subfamily C member 27 isoform 2-like | 1.2E-81 | 93 | |
Smp_157780.1 | DnaJ homolog subfamily A member 3, isoform 2-like | 2.3E-06 | 34 | Sjp_0055630 | DnaJ (Hsp40) homolog, subfamily C, member 16-like | 1.9E-18 | 52.1 | MS3_0015223.1 | Chain A, DnaJ homolog subfamily A member 3-like | 9.2E-121 | 88.8 | |
Smp_005070.1 | Chain A, DnaJ homolog subfamily A member 1-like | Â | Â | Sjp_0016830 | DnaJ protein homolog-like | 7.1E-11 | 44.8 | MS3_0014016.1 | DnaJ homolog subfamily A member 1 isoform 1-like | 4.3E-63 | 85.2 | |
Smp_332220.1 | Chain A, DnaJ homolog subfamily A member 3-like | Â | Â | Sjp_0055630 | DnaJ (Hsp40) homolog, subfamily C, member 16-like | 1.8E-18 | 52.1 | MS3_0015223.1 | Chain A, DnaJ homolog subfamily A member 3-like | 8.4E-121 | 88.8 | |
Smp_305770.1 (Smp_132040) | DnaJ homolog subfamily C member 28-like | Â | Â | Sjp_0088410 | Chain A, DnaJ homolog subfamily A member 3-like | 2.7E-19 | 59.7 | MS3_0015265.1 | DnaJ homolog subfamily C member 28-like | 7.4E-118 | 92.9 | |
Smp_344590.1 (Smp_153360) | DnaJ homolog subfamily B member 8-like | Â | Â | Sjp_0031300 | DnaJ (Hsp40) homolog, subfamily C, member 5-like | 4.5E-08 | 39.1 | MS3_0012731.1 | No hit | 6.7E-45 | 83.1 | |
Smp_323770.1 | DnaJ homolog subfamily C member 12 isoform b-like | Â | Â | Sjp_0103030 | DnaJ homolog subfamily C member 12 isoform a-like | 6.7E-43 | 69.4 | MS3_0012915.1 | Chain SP, 40S ribosomal protein S15-like | 1.6E-08 | 34.3 | |
Smp_327150.1 | DnaJ homolog subfamily C member 13 isoform 2-like | Â | Â | Sjp_0002640 | DnaJ homolog subfamily C member 13 isoform 2-like | 6.2E-166 | 93.5 | MS3_0018783.1 | DnaJ homolog subfamily C member 13 isoform 2-like | 0 | 86.1 | |
Smp_243870.1 | DnaJ (Hsp40) homolog subfamily C member 16-like | Â | Â | Sjp_0055630 | DnaJ (Hsp40) homolog, subfamily C, member 16-like | 7.9E-162 | 89 | MS3_0011723.1 | DnaJ (Hsp40) homolog, subfamily C, member 16-like | 0 | 93.1 | |
Smp_346200.1 (Smp_173390) | DnaJ homolog subfamily C member 1 precursor-like | Â | Â | Sjp_0097410 | DnaJ homolog subfamily C member 1-like | 2.3E-131 | 86.8 | MS3_0014178.1 | DnaJ homolog subfamily C member 1 precursor-like | 2.0E-116 | 97.7 | |
Smp_210160.1 | DnaJ homolog subfamily A member 4 isoform 1-like | Â | Â | Sjp_0043160 | Chain A, DnaJ homolog subfamily B member 12-like | 1.5E-34 | 68.7 | MS3_0014114.1 | DnaJ homolog subfamily A member 4 isoform 1-like | 1.4E-52 | 85.3 | |
HSP 70 | Smp_303400.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 84.9 | Sjp_0044680 | Heat shock 70Â kDa protein 8 isoform 1 variant-like | 1.1E-88 | 89.1 | MS3_0019576.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 96.7 |
Smp_303390.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 84.9 | Sjp_0044680 | Heat shock 70Â kDa protein 8 isoform 1 variant-like | 8.2E-89 | 89.1 | MS3_0019576.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 96.5 | |
Smp_303410.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 84.9 | Sjp_0044680 | Heat shock 70Â kDa protein 8 isoform 1 variant-like | 1.1E-88 | 89.1 | MS3_0019576.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 96.7 | |
Smp_303550.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 84.9 | Sjp_0044680 | Heat shock 70Â kDa protein 8 isoform 1 variant-like | 1.1E-88 | 89.1 | MS3_0019576.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 96.7 | |
Smp_303420.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 84.9 | Sjp_0044680 | Heat shock 70Â kDa protein 8 isoform 1 variant-like | 1.1E-88 | 89.1 | MS3_0019576.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 96.7 | |
Smp_302180.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 84.9 | Sjp_0044680 | Heat shock 70Â kDa protein 8 isoform 1 variant-like | 1.1E-88 | 89.1 | MS3_0019576.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 96.7 | |
Smp_302170.1 (Smp_106930) | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 84.9 | Sjp_0044680 | Heat shock 70Â kDa protein 8 isoform 1 variant-like | 1.1E-88 | 89.1 | MS3_0019576.1 | Heat shock cognate 71Â kDa protein isoform 1-like | 0 | 96.7 | |
Smp_049550.1 | Endoplasmic reticulum chaperone BiP precursor-like | 2.8E-63 | 72.9 | Sjp_0010400 | HSPA5 protein-like | 1.5E-135 | 93.7 | MS3_0019661.1 | Endoplasmic reticulum chaperone BiP precursor-like | 0 | 94.3 | |
Smp_106130.1 | HSPA9 protein-like | 6.0E-41 | 66.7 | Sjp_0026230 | Stress-70 protein, mitochondrial precursor-like | 0 | 94.7 | MS3_0013933.1 | Stress-70 protein, mitochondrial precursor-like | 0 | 98.3 | |
Smp_088950 | HYOU1 protein-like | Â | Â | Sjp_0060680 | Hypoxia up-regulated protein 1 precursor-like | 0 | 86.2 | MS3_0014894.1 | Hypoxia up-regulated 1-like | 0 | 93 | |
Smp_072320 | Chain A, Heat shock Cognate 71Â kDa protein-like | Â | Â | Sjp_0010400 | HSPA5 protein-like | 5.2E-15 | 53.4 | MS3_0018966.1 | Heat shock 70Â kDa protein 4L isoform 4-like | 7.60E-03 | 30.3 | |
Smp_069130 | Heat shock 70Â kDa protein 4L isoform 2-like | Â | Â | Sjp_0017890 | Chain A, HSP 105Â kDa-like | 2.1E-135 | 82.3 | MS3_0018966.1 | Heat shock 70Â kDa protein 4L isoform 4-like | 0 | 93.8 | |
HSP 90 | Smp_072330.1 | HSP 90-alpha isoform 2-like | 1.3E-102 | 76.1 | Sjp_0044660 | HSP 90-alpha isoform 2-like | 5.0E-117 | 87.8 | MS3_0014803.1 | Hsp90-alpha S52A bound to PU-11-trans-like | 5.0E-128 | 95.9 |
Smp_155740.1 | TRAP1 protein-like | 1.1E-80 | 55.6 | Sjp_0082320 | TRAP1-like | 0 | 89.3 | MS3_0012796.1 | TNF receptor associated protein 1-like | 0 | 96.6 | |
Smp_340630.1 (Smp_030300) | Endoplasmin precursor-like | 2.4E-49 | 54.6 | Sjp_0012140 | Endoplasmin precursor-like | 4.4E-176 | 94.2 | MS3_0013183.1 | Endoplasmin precursor-like | 2.1E-175 | 94.9 | |