Efficacy of two topical fluralaner formulations (Bravecto®; Bravecto® Plus) against Asian longhorned tick (Haemaphysalis longicornis) infestations of cats

Table 2 Comparison between of least square mean estimates of live Haemaphysalis longicornis tick counts (10 cats per treatment group)

Day of counts	Control vs. fluralaner				Control vs. fluralaner + moxidectin
Day of counts	Estimate	Standard error	Test statistic	P-value	Estimate	Standard error	Test statistic	P-value
Study 1
2	17.4	2.8	t₁₇ = 6.28	< 0.0001	17.4	2.8	t₁₇ = 6.28	< 0.0001
30	32.9	5.5	t₁₈ = 5.93	< 0.0001	32.9	5.5	t₁₈ = 5.93	< 0.0001
60	24.0	3.3	t₁₈ = 7.21	< 0.0001	24.0	3.3	t₁₈ = 7.21	< 0.0001
90	22.6	3.8	t₁₈ = 6.00	< 0.0001	23.6	3.7	t₁₈ = 6.38	< 0.0001
Study 2
2^a	12.5	3.1			12.5	3.1
30	34.8	3.6	t₁₈ = 9.68	< 0.0001	34.8	3.6	t₁₈ = 9.68	< 0.0001
60	20.2	3.3	t₁₈ = 6.18	< 0.0001	20.4	3.3	t₁₈ = 6.26	< 0.0001
90	21.6	3.0	t₁₈ = 7.26	< 0.0001	21.6	3.0	t₁₈ = 7.26	< 0.0001

^aFor statistical comparisons, the protocol requirement for each study was that at least six cats in the control group had to be adequately infested with live H. longicornis ticks (≥ 13 ticks). At this time point in Study 2, only three control group cats had adequate infestations

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