Table 1 Top 50 proteins identified by mass spectrometry from 100k extracellular vesicles isolated from adult Fasciola gigantica culture supernatants
Accession no. | Description | Unique peptides | Molecular weight (kDa) | pI |
|---|---|---|---|---|
A0A504YKS2 | Dynein heavy chain 1 cytosolic | 66 | 540.7 | 6.44 |
A0A4E0S279 | Otoferlin | 59 | 242.6 | 6.05 |
A0A504YEK9 | Transient receptor potential cation channel subfamily Mmember 2 | 50 | 200.2 | 7.23 |
A0A4E0RXP6 | Myoferlin | 37 | 179.1 | 6.3 |
A0A4E0RX62 | Programmed cell death 6-interacting protein | 37 | 86.3 | 5.81 |
A0A504Z6J5 | Receptor Mediated Endocytosis | 37 | 62.2 | 6.98 |
A0A504Z0R7 | Vacuolar protein-sorting-associated protein 4 | 37 | 49 | 8.53 |
A0A504YKR3 | Serine/threonine-protein kinase PAK | 36 | 54.2 | 8.03 |
C6KGZ9 | Leucine amino peptidase | 32 | 56.3 | 7.62 |
A0A504YLZ2 | Uncharacterized protein | 32 | 113.3 | 6.77 |
B1NI97 | Heat shock protein 70 | 29 | 70.7 | 5.74 |
A0A4E0R767 | Putative cytosolic ca2 + -dependent cysteine protease calpain | 29 | 88.9 | 7.17 |
A0A4E0RJT9 | Calpain-B | 28 | 85.7 | 5.6 |
A0A504Y4G4 | Long-chain-fatty-acid-CoA ligase | 28 | 76.6 | 8.43 |
A0A2H1BY53 | Phosphopyruvate hydratase | 27 | 61.3 | 7.4 |
A0A2H1C3P3 | 14-3-3 protein | 26 | 28 | 5.3 |
A0A504YH77 | Malic enzyme | 26 | 63.7 | 8.18 |
A0A504YP52 | Annexin | 26 | 101.3 | 6.58 |
A0A504YZD9 | Translation elongation factor 2 | 26 | 94.6 | 6.93 |
A0A504YRB3 | BRO1 domain and CAAX motif containing | 25 | 48.6 | 7.31 |
A0A504YS13 | Hepatocyte growth factor-regulated tyrosine kinase substrate | 24 | 85.6 | 6.65 |
A0A504YKC9 | Fatty-acid amide hydrolase 1 | 24 | 69.6 | 8.22 |
A0A504YB52 | Galectin | 24 | 123.6 | 6.86 |
A0A504Z9J2 | Serine/threonine kinase | 23 | 65.7 | 9.45 |
A0A504YJX4 | Autophagy-related protein 9 | 23 | 95.5 | 8.5 |
A0A4E0RG70 | Rab GDP dissociation inhibitor | 22 | 51.6 | 6.6 |
A0A504Z761 | Severin | 22 | 43.1 | 6.14 |
A0A504Z3L5 | Heat shock protein kDa | 22 | 69.8 | 7.56 |
A0A504YE87 | C2 domain | 22 | 134 | 6.3 |
A0A504Y6B9 | Uncharacterized protein | 21 | 36.8 | 9.23 |
A0A504YSL7 | L-plastin | 21 | 73.8 | 6.07 |
A0A504Z4Z3 | DnaJ like protein subfamily A member 1 | 21 | 44.8 | 6.84 |
A0A504YVC1 | Niemann-Pick C1 protein | 21 | 152.5 | 5.88 |
A0A504YUZ5 | Synaptosomal-associated protein 25-A | 20 | 27.1 | 6.54 |
A0A4E0S0V7 | Putative ankyrin repeat-containing | 20 | 88 | 6.58 |
A0A504X7M0 | Leukotriene A-4 hydrolase | 20 | 77.6 | 7.97 |
A0A504YNB9 | Charged multivesicular body protein | 20 | 68.4 | 5.52 |
A0A4E0S286 | Pcd6 interacting protein | 19 | 204.6 | 6.84 |
A0A504YZP0 | Carboxylic ester hydrolase | 19 | 78.9 | 6.57 |
A0A504YHJ1 | T-cell immunomodulatory protein | 19 | 70.3 | 5.1 |
A0A504YNI3 | STAM-binding protein A | 19 | 44 | 6.58 |
A0A504Y9P3 | Major vault protein isoform X1 | 19 | 99.7 | 5.48 |
A0A504YQE4 | Putative vacuolar protein sorting 26 vps26 | 18 | 60.7 | 5.91 |
A0A2H1CH07 | Rab-protein 8 | 18 | 25.3 | 6.09 |
A0A504Y734 | Putative spindle pole body protein | 18 | 39.4 | 5.06 |
A0A504YNN3 | Vacuolar protein sorting-associated protein VTA1 | 18 | 31.8 | 5.92 |
A0A504YUZ4 | Cyclin-Y | 18 | 51.8 | 7.84 |
Q45UT3 | Phosphoglycerate kinase | 18 | 47 | 8.87 |
A0A504YH94 | Band 3 anion transport protein | 18 | 113.6 | 8.43 |
A0A4E0R5U1 | Dynein heavy chain axonemal | 18 | 481.1 | 5.67 |