Efficacy of oral, topical and extended-release injectable formulations of moxidectin combined with doxycycline in Dirofilaria immitis naturally infected dogs

Table 2 Circulating antigen scores at enrolment (Days –15)

Dog number	Group 1 Moxidectin oral	Dog number	Group 2 Moxidectin Spot-On	Dog number	Group 3 Moxidectin injectable
1	+ +	1	+ +	1	+ +
2	+ +	2	+ +	2	+ +
3	+ +	3	+	3	-
4	+ +	4	+ +	4	+ +
5	+ +	5	+ +	5	-
6	+ +	6	+ +	6	+ +
7	+ +	7	+ +	7	+ +
8	+ +	8	+ +	8	+ +
9	+ +	9	+	9	+ +
10	+ +	10	+ +	10	+ +

ISSN: 1756-3305

Dog number	Group 1 Moxidectin oral	Dog number	Group 2 Moxidectin Spot-On	Dog number	Group 3 Moxidectin injectable
1	+ +	1	+ +	1	+ +
2	+ +	2	+ +	2	+ +
3	+ +	3	+	3	-
4	+ +	4	+ +	4	+ +
5	+ +	5	+ +	5	-
6	+ +	6	+ +	6	+ +
7	+ +	7	+ +	7	+ +
8	+ +	8	+ +	8	+ +
9	+ +	9	+	9	+ +
10	+ +	10	+ +	10	+ +

Dog number	Group 1 Moxidectin oral	Dog number	Group 2 Moxidectin Spot-On	Dog number	Group 3 Moxidectin injectable
1	+ +	1	+ +	1	+ +
2	+ +	2	+ +	2	+ +
3	+ +	3	+	3	-
4	+ +	4	+ +	4	+ +
5	+ +	5	+ +	5	-
6	+ +	6	+ +	6	+ +
7	+ +	7	+ +	7	+ +
8	+ +	8	+ +	8	+ +
9	+ +	9	+	9	+ +
10	+ +	10	+ +	10	+ +

Dog number	Group 1 Moxidectin oral	Dog number	Group 2 Moxidectin Spot-On	Dog number	Group 3 Moxidectin injectable
1	+ +	1	+ +	1	+ +
2	+ +	2	+ +	2	+ +
3	+ +	3	+	3	-
4	+ +	4	+ +	4	+ +
5	+ +	5	+ +	5	-
6	+ +	6	+ +	6	+ +
7	+ +	7	+ +	7	+ +
8	+ +	8	+ +	8	+ +
9	+ +	9	+	9	+ +
10	+ +	10	+ +	10	+ +