Insecticide resistance status of Aedes aegypti in southern and northern Ghana

Parasites & Vectors

Table 4 Distribution of tri-loci genotypes and their genetic association with insecticide resistance phenotypes

Insecticide	phenotype	CC/II/VV	OR(95% CI	P	CC/II/LL	OR(95% CI	P	CC/VV/VV	OR(95% CI	P
Permethrin	R	45	5.96(2.6- 13.7)	0.000^*	9	7.02(1.3–68.5)	0.008*	0	nd	nd
Permethrin	S	28	5.96(2.6- 13.7)	0.000^*	2	7.02(1.3–68.5)	0.008*	0	nd	nd
Deltamethrin	R	44	1.97(0.8–5.3)	0.148	5	1.28(0.3- 5.3)	0.68	3	1.54(1.97- 11.92)	0.68
Deltamethrin	S	57	1.97(0.8–5.3)	0.148	6	1.28(0.3- 5.3)	0.68	3	1.54(1.97- 11.92)	0.68
DDT	R	39	na		12	na	Na	1	na	na
DDT	S	Na	na			na	Na		na	na

Each tri-locus genotyped is named according to the genotypic composition at each kdr mutation following the order 410 (VV, VL or LL)/1016 (VV, VI or II)/1534 (FF, FC or CC). VV wild type (susceptible); LL mutant (resistant); II mutant (resistant); CC mutant (resistant), OR odds ratio, CI confidence interval, DDT dichlorodiphenyltrichloroethane, nd not determined, na not applicable because the group was not genotyped, P P-value (Fisher’s exact), *P < 0.05(significant). CI Confidence interval

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