Table 3 Relationship between the ace-1 mutant gene and insecticide resistance in An. sinensis
From: Insecticide resistance of Anopheles sinensis after elimination of malaria in Henan Province, China
Sampling sites/populations | Insecticides | Statusa | Sample size (n) | ace-1 genotype (n)b | Allelic gene frequency | Odds ratio (95% CI) G119S | |||
|---|---|---|---|---|---|---|---|---|---|
G/G | S/S | G/S | G119G, n (%) | G119S, n (%) | |||||
Pingqiao | Propoxur | CR | 18 | 4 | 4 | 10 | 18 (50.00) | 18 (50.00) | 0.52 (0.23, 1.20) |
S | 32 | 0 | 10 | 22 | 22 (34.38) | 42 (65.63) | |||
Malathion | CR | 2 | 0 | 1 | 1 | 1 (25.00) | 3 (75.00) | 4.75(0.47, 48.34) | |
S | 31 | 7 | 0 | 24 | 38 (61.29) | 24 (38.71) | |||
Total | – | 83 | 11 | 15 | 57 | 79 (47.59) | 87 (52.41) | – | |
Tanghe | Propoxur | CR | 7 | 0 | 1 | 6 | 6 (42.86) | 8 (57.14) | 17.33* (2.91, 103.38) |
S | 14 | 12 | 0 | 2 | 26 (92.86) | 2 (7.14) | |||
Malathion | CR | 1 | 0 | 0 | 1 | 1 (50.00) | 1 (50.00) | 37.00* (1.22, 1119.83) | |
S | 19 | 18 | 0 | 1 | 37 (97.37) | 1 (2.63) | |||
Total | – | 41 | 30 | 1 | 10 | 70 (85.37) | 12 (14.63) | – | |
Xiangcheng | Propoxur | CR | 33 | 29 | 0 | 4 | 62 (93.94) | 4 (6.06) | 3.81(0.41, 35.05) |
S | 30 | 29 | 0 | 1 | 59 (98.33) | 1 (1.67) | |||
Malathion | CR | 1 | 0 | 0 | 1 | 1 (50.00) | 1 (50.00) | 20.33(1.00, 410.20) | |
S | 32 | 29 | 0 | 3 | 61 (95.31) | 3 (4.69) | |||
Total | – | 96 | 87 | 0 | 9 | 183 (95.31) | 9 (4.69) | – | |
Xiangfu | Propoxur | CR | 32 | 0 | 4 | 28 | 28 (43.75) | 36 (56.25) | 1.50(0.60, 3.75) |
S | 13 | 1 | 0 | 12 | 14 (53.85) | 12 (46.15) | |||
Malathion | CR | 18 | 0 | 5 | 13 | 13 (36.11) | 23 (63.89) | 1.66 (0.72, 3.84) | |
S | 32 | 2 | 3 | 27 | 31 (48.44) | 33 (51.56) | |||
Total | – | 95 | 3 | 12 | 80 | 86 (45.26) | 104 (54.74) | – | |
Total | – | – | 315 | 131 | 28 | 156 | 418 (66.35) | 212 (33.65) | – |