Fluralaner (Bravecto®) treatment kills Aedes aegypti after feeding on Dirofilaria immitis-infected dogs

Parasites & Vectors

Table 4 Live mosquitoes, mosquitoes with Dirofilaria immitis (Di) third-stage larvae, and mosquitoes with D. immitis PCR-positive counts 2 weeks after each mosquito challenge^a

Challenge day	Number of live mosquitoes	Number with Di third-stage larvae	Number PCR-positive for Di
−7
Control	19	3	13
Fluralaner	39	6	29
2
Control	7	2	7
Fluralaner	0	NA	NA
30
Control	8	3	5
Fluralaner	1	0	0
56
Control	7	0	6
Fluralaner	0	NA	NA
84
Control	12	1	12
Fluralaner	4	0	0

Day −7 was prior to treatment administration
NA not applicable
^aOne non-treated dog stayed microfilaria-negative throughout, leading to improved mosquito survival; data from this dog were not included in the above calculations

ISSN: 1756-3305