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Fig. 6 | Parasites & Vectors

Fig. 6

From: Inhibition of GSDMD-mediated pyroptosis triggered by Trichinella spiralis intervention contributes to the alleviation of DSS-induced ulcerative colitis in mice

Fig. 6

Pyroptosis inhibitor vx-765 relieved DSS-induced colitis. a The body weight changes in DSS-induced colitis after pyroptosis inhibitor belnacasan (vx-765) and pyroptosis agonist nigericin (NSC) interventions. b Colonic length in all the experimental groups were measured and recorded. c Histopathological changes in colonic samples were examined by H&E staining and were measured by evaluating its therapeutic effect. d Cytokines of IL-6, TGF-β, IL-4 and IL-10 were measured. All the results are presented as mean ± SD, and statistics symbols used are: *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001

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Parasites & Vectors

ISSN: 1756-3305

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