Transcriptional variation in Babesia gibsoni (Wuhan isolate) between in vivo and in vitro cultures in blood stage

Table 1 Unigenes showing significantly different transcription levels in B. gibsoni (Wuhan isolate) blood-stage development between in vivo and in vitro cultured groups

DEGs	Transcript ID	Product annotation	Log2 fold change
Upregulated DEGs	TRINITY_GG_16_c41_g1	Merozoite surface protein 2	7.70
	TRINITY_GG_7_c11_g2	Spherical body protein 3	4.23
	TRINITY_GG_2_c55_g2	Microneme protein14	2.32
	TRINITY_GG_3_c127_g1	AP2 domain transcription factor	2.06
	TRINITY_GG_2_c139_g2	Calcium-dependent protein kinase 4	1.70
	TRINITY_GG_3_c159_g2	AP2 domain transcription factor	1.26
Downregulated DEGs	TRINITY_GG_2_c226_g2	Thioredoxin family protein, putative	−3.73
	TRINITY_GG_2_c163_g2	Cyclin-dependent kinase binding protein, putative	−3.65
	TRINITY_GG_16_c43_g1	T-complex protein 1	−2.51
	TRINITY_GG_2_c61_g5	AP2 domain transcription factor	−1.92
	TRINITY_GG_3_c199_g1	TPR domain-containing protein	−1.65
	TRINITY_GG_3_c219_g1	Hook-associated protein 2	−1.45
	TRINITY_GG_2_c74_g1	Zinc finger protein, putative	−1.25
	TRINITY_GG_16_c69_g2	AP2 domain transcription factor	−1.22

ISSN: 1756-3305