Metabolomics analysis of visceral leishmaniasis based on urine of golden hamsters

Parasites & Vectors

Table 1 Distribution numbers of identified metabolites

(A) Numbers of metabolites of different confidence levels
Detection mode	Total ions	Ions with RSD ≤ 30%	Roughly identified^a	MS interpreted^a	MS2 interpreted^a
ESI+	11,524	11,038	4886	5511	641
ESI−	7463	7163	3188	3632	343

(B) Numbers of differential metabolites at different time points (FC ≥ 1.2 or ≤ 0.8333, p < 0.05 and VIP ≥ 1.0)
Detection mode	Time points		Total
Detection mode	4 WPI	12 WPI	Total
ESI+	57	47	104
ESI−	33	18	51
Total	90	65	155

^aConfidence level of metabolites is in accord with the Metabolomics Standards Initiative (MSI) [35]. Roughly identified: metabolites of level 5; MS interpreted: the metabolites of level 4; MS2 interpreted: the metabolites of level 1–3

ISSN: 1756-3305