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Table 4 Total eggs laid by individual adult mosquitoes post continued exposure to different concentrations of ivermectin at the larval stages

From: Effects of larval exposure to sublethal doses of ivermectin on adult fitness and susceptibility to ivermectin in Anopheles gambiae s.s.

Ivermectin concentration (ppm)

Mean total eggs laid (95%CI)

Coefficient (SE)

95% CI

p-value

L1/L2

 0 (Control)

49.72 (42.04–57.40

Ref

  

 0.00001

47.27 (40.26–54.27)

− 2.45 (5.06)

− 12.40–7.50

0.63

 0.0001

46.46 (40.28–52.64)

− 3.26 (5.03)

− 13.15–6.63

0.52

L3/L4

 0 (Control)

40.42 (33.23–47.62)

Ref

  

 0.00001

35.42 (28.88–41.95

− 5.01 (4.84)

− 14.54–4.52

0.30

 0.0001

45.97 (39.31–52.63)

5.54 (4.95)

− 4.20–15.29

0.26

  1. Generalized linear regression, dependent variable total eggs laid, independent variables ivermectin concentration (indicator) and biological replicate, clustered by technical replicate (n = 3). Total eggs laid (unhatched eggs plus hatched eggs)
  2. L1/L2 1st/2nd instar larvae, L3/L4 3rd/4th instar larvae, ppm part per million, SE standard error, CI confidence interval