Fig. 2
From: Multilayer omics reveals the molecular mechanism of early infection of Clonorchis sinensis juvenile
Gross observation and histopathological changes of liver in mice infected with Clonorchis sinensis at different time points. a Gross morphology of livers. Inflammatory nodules are marked by thin black arrows. b Liver sections of C. sinensis-infected mice were stained with H&E staining (× 100). Red arrows and heavy black arrows represent adult worms and inflammatory cell infiltration, respectively. c Liver sections were prepared for Masson trichrome staining (× 100). Red, green and blue arrows indicate C. sinensis juvenile, biliary epithelial hyperplasia and collagen deposition, respectively. d Percentage of collagen fiber area in liver tissue. e Ishak score of Masson staining. Data are shown as mean ± SD (n = 3). *P < 0.05