Fig. 4

Comparative analysis of DEGs and changes of main signaling pathways in mouse liver induced by Clonorchis sinensis infection at different time points. a Heatmap and hierarchical clustering of DEGs. Red and blue represent genes up- and downregulated, respectively. b–f KEGG pathway enrichment analysis of the identified DEGs between 6 and 0 h groups, 18 h and 0 h groups, 24 h and 0 h groups, 3 d and 0 h groups and 7 d and 0 h groups, respectively. The top 20 most-enriched pathways are shown