Fig. 5

PbMAP1-specific antibodies generated protective immunity against Plasmodium berghei ANKA. A, B BALB/c mice without any immunization (control) exhibited 1.70-fold higher parasitemia than PbMAP1 peptide-immunized mice on day 11 post-infection; the error bars indicate SD. Mice immunized with PbMAP1 peptides survived 6 days longer than control mice. C, D Mice injected with serum from a normal infected mouse exhibited 1.86-fold higher parasitemia than those injected with anti-PbMAP1 sera on day 11 post-infection. Compared with the normal mouse serum group, the anti-PbMAP1 serum group survived for 6 days longer; the error bars indicate SD