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Fig. 1 | Parasites & Vectors

Fig. 1

From: Elicitation of T-cell-derived IFN-γ-dependent immunity by highly conserved Plasmodium ovale curtisi Duffy binding protein domain region II (PocDBP-RII)

Fig. 1

Schematic illustration of the experimental process. Genomic DNA was extracted from blood samples of patients infected with Plasmodium ovale curtisi. Genetic polymorphisms and natural selection of PocDBP-RII gene were investigated by sequencing and neutral tests. Copy number variation of PocDBP-RII gene was studied by qPCR. The proliferation of lymphocytes in mice immunized with rPocDBP-RII was determined using the CCK8 assay. Levels of anti-rPocDBP-RII antibody response in serum and IFN-γ/IL-10-producing T cells in spleens of immunized mice were assessed by protein microarrays and flow cytometry, respectively

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Parasites & Vectors

ISSN: 1756-3305

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