Fig. 2

NTA and TEM analyses of caecum-derived EVs (cEVs) isolated from E. falciformis infected-mice during the early hour (< 1 h) of oocyst ingestion, first merozont generation (68 hpi), second merozont generation (116 hpi), latent period of oocyst shedding in the host faeces (7 dpi) and the onset of host recovery from the infection (10 dpi). An equivalent of 10 µg and 10 µl of cEVs was used for the NTA and TEM respectively. cEVs, Caecum-derived extracellular vesicles; dpi, days post-infection; hpi, hours post-infection; NTA, nanoparticle tracking analysis; TEM, transmission electronic microscopy